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- Title
Monitoring of hemodynamic changes induced in the healthy breast through inspired gas stimuli with MR-guided diffuse optical imaging.
- Authors
Carpenter, C M; Rakow-Penner, R; Jiang, S; Pogue, B W; Glover, G H; Paulsen, K D
- Abstract
The modulation of tissue hemodynamics has important clinical value in medicine for both tumor diagnosis and therapy. As an oncological tool, increasing tissue oxygenation via modulation of inspired gas has been proposed as a method to improve cancer therapy and determine radiation sensitivity. As a radiological tool, inducing changes in tissue total hemoglobin may provide a means to detect and characterize malignant tumors by providing information about tissue vascular function. The ability to change and measure tissue hemoglobin and oxygenation concentrations in the healthy breast during administration of three different types of modulated gas stimuli (oxygen/ carbogen, air/carbogen, and air/oxygen) was investigated.
- Publication
Medical physics, 2010, Vol 37, Issue 4, p1638
- ISSN
0094-2405
- Publication type
Journal Article
- DOI
10.1118/1.3358123