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- Title
Compositional breast imaging using a dual-energy mammography protocol.
- Authors
Laidevant, Aurelie D; Malkov, Serghei; Flowers, Chris I; Kerlikowske, Karla; Shepherd, John A
- Abstract
Mammography has a low sensitivity in dense breasts due to low contrast between malignant and normal tissue confounded by the predominant water density of the breast. Water is found in both adipose and fibroglandular tissue and constitutes most of the mass of a breast. However, significant protein mass is mainly found in the fibroglandular tissue where most cancers originate. If the protein compartment in a mammogram could be imaged without the influence of water, the sensitivity and specificity of the mammogram may be improved. This article describes a novel approach to dual-energy mammography, full-field digital compositional mammography (FFDCM), which can independently image the three compositional components of breast tissue: water, lipid, and protein.
- Publication
Medical physics, 2010, Vol 37, Issue 1, p164
- ISSN
0094-2405
- Publication type
Journal Article
- DOI
10.1118/1.3259715