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- Title
Next-generation sequencing: proof of concept for antenatal prediction of the fetal Kell blood group phenotype from cell-free fetal DNA in maternal plasma.
- Authors
Rieneck, Klaus; Bak, Mads; Jønson, Lars; Clausen, Frederik Banch; Krog, Grethe Risum; Tommerup, Niels; Nielsen, Leif Kofoed; Hedegaard, Morten; Dziegiel, Morten Hanefeld
- Abstract
Maternal immunization against KEL1 of the Kell blood group system can have serious adverse consequences for the fetus as well as the newborn baby. Therefore, it is important to determine the phenotype of the fetus to predict whether it is at risk. We present data that show the feasibility of predicting the fetal KEL1 phenotype using next-generation sequencing (NGS) technology.
- Publication
Transfusion, 2013, Vol 53, Issue 11 Suppl 2, p2892
- ISSN
1537-2995
- Publication type
Journal Article
- DOI
10.1111/trf.12172