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- Title
The challenges of measuring bleeding outcomes in clinical trials of platelet transfusions.
- Authors
Estcourt, Lise J; Heddle, Nancy; Kaufman, Richard; McCullough, Jeffrey; Murphy, Michael F; Slichter, Sherrill; Wood, Erica M; Stanworth, Simon J; Biomedical Excellence for Safer Transfusion Collaborative
- Abstract
Many platelet (PLT) transfusion trials now use bleeding as a primary outcome; however, previous studies have shown a wide variation in the amount (5%-70%) and type of bleeding documented. Differences in the way bleeding has been identified, recorded, and graded may account for some of this variability. This study's aim was to compare trials' method to document and grade bleeding.
- Publication
Transfusion, 2013, Vol 53, Issue 7, p1531
- ISSN
1537-2995
- Publication type
Journal Article
- DOI
10.1111/trf.12058