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Title
Impaired vascular KATP function attenuates exercise capacity in obese zucker rats.
Authors
Lu, Silu; Xiang, Lusha; Clemmer, John S; Gowdey, Andrew R; Mittwede, Peter N; Hester, Robert L
Abstract
Obese subjects exhibit decreased exercise capacity (VO2max ). We have shown that vascular KATP channel mediates arteriolar dilation to muscle contraction. We hypothesize that exercise capacity is decreased in obesity due to impaired vascular KATP function.
Publication
Microcirculation (New York, N.Y. : 1994), 2013, Vol 20, Issue 7, p662