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- Title
Additive effect of sirolimus and anti-death receptor 5 agonistic antibody against hepatocellular carcinoma.
- Authors
Kawahara, Toshiyasu; Toso, Christian; Yamaguchi, Keisuke; Cader, Sonia; Douglas, Donna N; Nourbakhsh, Mahra; Lewis, Jamie T; Churchill, Thomas A; Yagita, Hideo; Kneteman, Norman M
- Abstract
Despite careful patient selection, hepatocellular carcinoma (HCC) recurs in 10-20% of cases after liver transplantation, and the use of potent adjuvant anticancer drugs would be welcome. The aim of this study was to evaluate the efficiency of a combined therapy of rapamycin (sirolimus) and anti-death receptor (DR)5 monoclonal antibody (mAb) on HCC.
- Publication
Liver international : official journal of the International Association for the Study of the Liver, 2013, Vol 33, Issue 9, p1441
- ISSN
1478-3231
- Publication type
Journal Article
- DOI
10.1111/liv.12275