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- Title
Increased expression of mitochondrial proteins associated with autophagy in biliary epithelial lesions in primary biliary cirrhosis.
- Authors
Sasaki, Motoko; Miyakoshi, Masami; Sato, Yasunori; Nakanuma, Yasuni
- Abstract
We have reported the involvement of deregulated autophagy and subsequent cellular senescence in biliary epithelial lesions in primary biliary cirrhosis (PBC). Given that mitochondria are a major target of autophagy, we hypothesized that deregulated autophagy of mitochondria may be involved in autoimmune pathogenesis in PBC.
- Publication
Liver international : official journal of the International Association for the Study of the Liver, 2013, Vol 33, Issue 2, p312
- ISSN
1478-3231
- Publication type
Journal Article
- DOI
10.1111/liv.12049