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- Title
Intrahepatic mRNA levels of SOCS1 and SOCS3 are associated with cirrhosis but do not predict virological response to therapy in chronic hepatitis C.
- Authors
Pascarella, Stéphanie; Clément, Sophie; Dill, Michael T; Conzelmann, Stéphanie; Lagging, Martin; Missale, Gabriele; Neumann, Avidan U; Pawlotsky, Jean-Michel; Zeuzem, Stefan; Rubbia-Brandt, Laura; Bochud, Pierre-Yves; Negro, Francesco
- Abstract
Antiviral treatment of chronic hepatitis C is not invariably successful, costly and associated with serious side-effects, and therefore should be indicated only when the chances of benefitting patients exceed the potential risks. The suppressor of cytokine signalling (SOCS) family members have been suggested to affect the rate of virological response to therapy, but the published evidence is conflicting.
- Publication
Liver international : official journal of the International Association for the Study of the Liver, 2013, Vol 33, Issue 1, p94
- ISSN
1478-3231
- Publication type
Journal Article
- DOI
10.1111/liv.12031