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Title
In vitro assessment, using thrombin generation, of the applicability of prothrombin complex concentrate as an antidote for Rivaroxaban.
Authors
Dinkelaar, J; Molenaar, P J; Ninivaggi, M; de Laat, B; Brinkman, H J M; Leyte, A
Abstract
Rivaroxaban has been approved as an antithrombotic agent for prevention of venous thromboembolism with specific indications. At present no antidote is appointed and no guidelines have been formulated for the measurement of Rivaroxaban reversal.
Publication
Journal of thrombosis and haemostasis : JTH, 2013, Vol 11, Issue 6, p1111