We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Characterizing polymorphisms and allelic diversity of von Willebrand factor gene in the 1000 Genomes.
- Authors
Wang, Q Y; Song, J; Gibbs, R A; Boerwinkle, E; Dong, J F; Yu, F L
- Abstract
The von Willebrand factor (VWF) gene is highly polymorphic, with variants correlated with VWF antigen levels, adhesion activity, clearance and factor VIII binding. VWF mutations are detected in patients with von Willebrand disease (VWD), whereas polymorphic variants could be associated with thrombosis. However, information on the ethnic diversity of VWF variants and their association with diseases is limited.
- Publication
Journal of thrombosis and haemostasis : JTH, 2013, Vol 11, Issue 2, p261
- ISSN
1538-7836
- Publication type
Journal Article
- DOI
10.1111/jth.12093