We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Gene × smoking interactions on human brain gene expression: finding common mechanisms in adolescents and adults.
- Authors
Wolock, Samuel L; Yates, Andrew; Petrill, Stephen A; Bohland, Jason W; Blair, Clancy; Li, Ning; Machiraju, Raghu; Huang, Kun; Bartlett, Christopher W
- Abstract
Numerous studies have examined gene × environment interactions (G × E) in cognitive and behavioral domains. However, these studies have been limited in that they have not been able to directly assess differential patterns of gene expression in the human brain. Here, we assessed G × E interactions using two publically available datasets to assess if DNA variation is associated with post-mortem brain gene expression changes based on smoking behavior, a biobehavioral construct that is part of a complex system of genetic and environmental influences.
- Publication
Journal of child psychology and psychiatry, and allied disciplines, 2013, Vol 54, Issue 10, p1109
- ISSN
1469-7610
- Publication type
Journal Article
- DOI
10.1111/jcpp.12119