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- Title
Osteoarthritis of the knee and hip. Part II: therapy with ibuprofen and a review of clinical trials.
- Authors
Adatia, Aleem; Rainsford, K D; Kean, Walter F
- Abstract
We review the pharmacological properties and clinical evidence pertaining to the efficacy of ibuprofen as a first-line treatment in hip and knee osteoarthritis (OA). In the context of our previous paper's exploration of the aetiology and pathogenesis of OA as a basis for pharmacotherapy, we discuss the pharmacokinetics (PK) and clinical pharmacodynamics (PD) of ibuprofen relevant to OA.
- Publication
The Journal of pharmacy and pharmacology, 2012, Vol 64, Issue 5, p626
- ISSN
2042-7158
- Publication type
Journal Article
- DOI
10.1111/j.2042-7158.2012.01456.x