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- Title
Factor XIII Val34Leu mutation accelerates the development of fibrosis in patients with chronic hepatitis B and C.
- Authors
Dik, Kathelijne; de Bruijne, Joep; Takkenberg, R Bart; Roelofs, Joris J; Tempelmans, Marjan J; Dijkgraaf, Marcel G W; Gelderblom, Huub C; Reesink, Henk W; Meijers, Joost C M; Jansen, Peter L; Levi, Marcel
- Abstract
There is considerable variation in liver fibrosis stage and progression to cirrhosis among patients with chronic hepatitis B (CHB) or C (CHC). Coagulation pathway activity due to genetic variations could influence the rate of fibrosis. We investigated thrombotic risk factors and their association with the extent and progression of fibrosis in CHB or CHC patients.
- Publication
Hepatology research : the official journal of the Japan Society of Hepatology, 2012, Vol 42, Issue 7, p668
- ISSN
1872-034X
- Publication type
Journal Article
- DOI
10.1111/j.1872-034X.2011.00963.x