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- Title
Genetic polymorphisms as determinants for disease-preventive effects of vitamin E.
- Authors
Zingg, Jean-Marc; Azzi, Angelo; Meydani, Mohsen
- Abstract
Polymorphisms in genes involved in vitamin E uptake, distribution, metabolism, and molecular action may be important determinants for the protective effects of vitamin E supplementation. The haptoglobin 2-2 polymorphism is associated with increased production of oxygen free radicals and reduces levels of vitamin E and C; the consequent elevated risk for cardiovascular disease can be prevented by vitamin E supplementation.
- Publication
Nutrition reviews, 2008, Vol 66, Issue 7, p406
- ISSN
0029-6643
- Publication type
Journal Article
- DOI
10.1111/j.1753-4887.2008.00050.x