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- Title
L-theanine intervention enhances human gammadeltaT lymphocyte function.
- Authors
Bukowski, Jack F; Percival, Susan S
- Abstract
Human gammadeltaT lymphocytes are a subset of T cells and are a first line of defense against microbes and tumors. These gammadeltaT cells can be primed by nitrogen-containing bisphosphonates, and certain short-chain alkylamines. These primed gammadeltaT cells have an enhanced capacity to proliferate and to secrete cytokines upon ex vivo exposure to a wide variety of microbes and tumor cells. The largest dietary source of alkylamines is L-theanine, an amino acid unique to tea beverages that is catabolized to ethylamine. Supplementation of subjects with capsules containing L-theanine and catechins has recently been shown to decrease the incidence of cold and flu symptoms, while enhancing gammadeltaT cell function.
- Publication
Nutrition reviews, 2008, Vol 66, Issue 2, p96
- ISSN
0029-6643
- Publication type
Journal Article
- DOI
10.1111/j.1753-4887.2007.00013.x