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- Title
Polyunsaturated fatty acids and cardiovascular health.
- Authors
Kris-Etherton, Penny M; Hecker, Kari D; Binkoski, Amy E
- Abstract
Epidemiologic studies have shown a beneficial association between polyunsaturated fatty acid (PUFA), specifically linoleic acid (C18:2, n-6), intake and cardiovascular disease morbidity and mortality. Clinical studies have shown that n-6 PUFAs have the most potent cholesterol-lowering effects of the individual fatty acid classes, and emerging evidence suggests that PUFAs have favorable effects on postprandial lipemia. However, some studies suggest that high intakes of linoleic acid may have adverse effects on proinflammatory cytokines and adhesion molecules. Research is needed to establish the optimal level of dietary PUFAs that maximally affects the greatest number of health risk factors.
- Publication
Nutrition reviews, 2004, Vol 62, Issue 11, p414
- ISSN
0029-6643
- Publication type
Journal Article
- DOI
10.1111/j.1753-4887.2004.tb00013.x