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- Title
Short-chain 3-hydroxyacyl-CoA dehydrogenase is a negative regulator of insulin secretion in response to fuel and non-fuel stimuli in INS832/13 β-cells.
- Authors
Pepin, Emilie; Guay, Claudiane; Delghingaro-Augusto, Viviane; Joly, Erik; Madiraju, S R Murthy; Prentki, Marc
- Abstract
Hyperinsulinemia associated with non-ketotic hypoglycemia is observed in patients with mutated β-oxidation enzyme short-chain 3-hydroxyacyl-CoA dehydrogenase (HADHSC). In the present study, we investigated the mechanism underlying HADHSC-mediated regulation of insulin secretion.
- Publication
Journal of diabetes, 2010, Vol 2, Issue 3, p157
- ISSN
1753-0407
- Publication type
Journal Article
- DOI
10.1111/j.1753-0407.2010.00076.x