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- Title
The effect of fundoplication on proliferative and anti-apoptotic activity of esophageal mucosa in gastroesophageal reflux disease: 4-year follow-up study.
- Authors
Rantanen, Tuomo; Oksala, Niku; Honkanen, Teemu; Räsänen, Jari; Sihvo, Eero; Mattila, Jorma; Paimela, Hannu; Paavonen, Timo; Salo, Jarmo
- Abstract
The capacity of fundoplication to prevent esophageal adenocarcinoma is controversial. Development of cancer is associated with proliferation and anti-apoptosis, for which little data exist as to their response to fundoplication. Therefore, we wanted to clarify the effect of fundoplication on the magnitude of Ki-67 and B-cell lymphoma 2 (Bcl-2) during 48 months of follow up.
- Publication
Journal of digestive diseases, 2011, Vol 12, Issue 4, p263
- ISSN
1751-2980
- Publication type
Journal Article
- DOI
10.1111/j.1751-2980.2011.00508.x