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- Title
MChip, a low density microarray, differentiates among seasonal human H1N1, North American swine H1N1, and the 2009 pandemic H1N1.
- Authors
Heil, Gary L; McCarthy, Troy; Yoon, Kyoung-Jin; Liu, Siyuan; Saad, Magdi D; Smith, Catherine B; Houck, Julie A; Dawson, Erica D; Rowlen, Kathy L; Gray, Gregory C
- Abstract
The MChip uses data from the hybridization of amplified viral RNA to 15 distinct oligonucleotides that target the influenza A matrix (M) gene segment. An artificial neural network (ANN) automates the interpretation of subtle differences in fluorescence intensity patterns from the microarray. The complete process from clinical specimen to identification including amplification of viral RNA can be completed in <8 hours for under US$10.
- Publication
Influenza and other respiratory viruses, 2010, Vol 4, Issue 6, p411
- ISSN
1750-2659
- Publication type
Journal Article
- DOI
10.1111/j.1750-2659.2010.00185.x