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- Title
Physiological low dose of estrogen-protected neurons in experimental spinal cord injury.
- Authors
Samantaray, Supriti; Matzelle, Denise D; Ray, Swapan K; Banik, Naren L
- Abstract
A protective role for estrogen against neurodegeneration and neurotrauma has received enormous attention in recent years, unraveling multiple facets and thus establishing this steroid as a multiactive neuroprotectant. The present study briefly reports our findings on the neuroprotective efficacy of physiologically relevant low doses of estrogen in experimental spinal cord injury (SCI) in rats. The current finding further corroborates our earlier results on efficacy of pharmacological/supraphysiological levels of estrogen in SCI and adds to the significance of conducting preclinical studies on estrogen efficacy in SCI.
- Publication
Annals of the New York Academy of Sciences, 2010, Vol 1199, p86
- ISSN
1749-6632
- Publication type
Journal Article
- DOI
10.1111/j.1749-6632.2009.05360.x