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- Title
Epilepsy in the elderly.
- Authors
Leppik, Ilo E; Birnbaum, Angela K
- Abstract
The elderly, often defined as those 65 years or older, are the most rapidly growing segment of the population, and onset of epilepsy is higher in this age group than in any other. This paper reviews recent developments, including a new proposed definition of epilepsy, a transgenic mouse model of Alzheimer's disease that exhibits complex partial seizures, evidence that the highest incidence of epilepsy may occur after admission to a nursing home, a challenge to the vitamin D hypothesis of osteoporosis associated with antiepileptic drugs (AEDs), evidence that the genetic complement of hepatic isoenzymes is more predictive of metabolic rate than age, and data showing that there is considerable variability in serum levels of AEDs in many nursing home residents during constant dosing conditions.
- Publication
Annals of the New York Academy of Sciences, 2010, Vol 1184, p208
- ISSN
1749-6632
- Publication type
Journal Article
- DOI
10.1111/j.1749-6632.2009.05113.x