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- Title
Reperfusion and outcomes in Penumbra vs. systemic tissue plasminogen activator clinical trials.
- Authors
Alexandrov, Andrei V; Schellinger, Peter D; Saqqur, Maher; Barreto, Andrew; Demchuk, Andrew M; Ribo, Marc; Rubiera, Marta; Sharma, Vijay K; Heliopoulos, Ioannis; Alexandrov, Anne W; Molina, Carlos A; Tsivgoulis, Georgios; CLOTBUST and TUCSON Investigators
- Abstract
An uncontrolled clinical study of the Penumbra(™) system showed high rates of recanalisation and relatively poor functional outcomes that were inadequately compared with historic controls. We aimed to compare the findings in Penumbra with intravenous tissue plasminogen activator trials that determined recanalisation (Combined Lysis Of Thrombus in Brain ischaemia using transcranial Ultrasound and Systemic tissue plasminogen activator and Transcranial Ultrasound in Clinical Sonothrombolysis).
- Publication
International journal of stroke : official journal of the International Stroke Society, 2011, Vol 6, Issue 2, p118
- ISSN
1747-4949
- Publication type
Journal Article
- DOI
10.1111/j.1747-4949.2010.00559.x