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- Title
Mosaicism in autosomal dominant polycystic kidney disease revealed by genetic testing to enable living related renal transplantation.
- Authors
Connor, A; Lunt, P W; Dolling, C; Patel, Y; Meredith, A L; Gardner, A; Hamilton, N K; Dudley, C R K
- Abstract
Patients with end-stage renal disease (ESRD) secondary to autosomal dominant polycystic kidney disease (ADPKD) receive fewer living-related kidney (LRK) transplants than other groups with ESRD. This relates to the difficulties in excluding the disease in potential donors. We report a case which highlights these difficulties and, by discovery of mosaicism for a new mutation, illustrates the role of clinical and molecular genetic resources in assessing young related kidney donors for patients with ADPKD.
- Publication
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2008, Vol 8, Issue 1, p232
- ISSN
1600-6143
- Publication type
Journal Article
- DOI
10.1111/j.1600-6143.2007.02030.x