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- Title
Effect on the production of soluble endoglin from human choriocarcinoma cells by preeclampsia sera.
- Authors
Aoki, Youichi; Yamamoto, Tatsuo; Fumihisa, Chishima; Nakamura, Akikazu; Asanuma, Aki; Suzuki, Manami
- Abstract
The soluble endoglin (sEng) is an antiangiogenic protein that may inhibit TGF-β1 signaling and endothelial nitric oxide synthase activation in endothelial cells. The levels of sEng increased in sera obtained from preeclampsia. The factors that increase the sEng in preeclampsia have not been known well. To investigate the factors that may increase sEng in preeclampsia, we examined the effect of preeclampsia sera on the production of sEng from human choriocarcinoma (JEG-3) cells.
- Publication
American journal of reproductive immunology (New York, N.Y. : 1989), 2012, Vol 67, Issue 5, p413
- ISSN
1600-0897
- Publication type
Journal Article
- DOI
10.1111/j.1600-0897.2011.01086.x