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- Title
Focal increases of fetal macrophages in placentas from pregnancies with histological chorioamnionitis: potential role of fibroblast monocyte chemotactic protein-1.
- Authors
Toti, Paolo; Arcuri, Felice; Tang, Zhonghua; Schatz, Frederick; Zambrano, Eduardo; Mor, Gil; Niven-Fairchild, Tracy; Abrahams, Vikki M; Krikun, Graciela; Lockwood, Charles J; Guller, Seth
- Abstract
Histopathological chorioamnionitis (HCA) is caused by microbial-driven infiltration of leukocytes to the maternal-fetal interface resulting in adverse neonatal outcomes in a subset of pregnancies. The role of placental villus macrophages (i.e. Hofbauer cells, HBCs) in the pathophysiology of HCA is unelucidated.
- Publication
American journal of reproductive immunology (New York, N.Y. : 1989), 2011, Vol 65, Issue 5, p470
- ISSN
1600-0897
- Publication type
Journal Article
- DOI
10.1111/j.1600-0897.2010.00927.x