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- Title
Activation of TLR3 in the trophoblast is associated with preterm delivery.
- Authors
Koga, Kaori; Cardenas, Ingrid; Aldo, Paulomi; Abrahams, Vikki M; Peng, Bing; Fill, Sara; Romero, Roberto; Mor, Gil
- Abstract
Toll-like receptors (TLRs) recognize conserved sequences on the surface of pathogens and trigger effector cell functions. Previously, we described the expression of TLR3 by human trophoblast and their ability to respond to (Poly[I:C]). Here we evaluate the effect of Poly[I:C] on mouse pregnancy and characterize the local and systemic response.
- Publication
American journal of reproductive immunology (New York, N.Y. : 1989), 2009, Vol 61, Issue 3, p196
- ISSN
1600-0897
- Publication type
Journal Article
- DOI
10.1111/j.1600-0897.2008.00682.x