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- Title
Spectroscopic assessment of dermal melanin using blue vitiligo as an in vivo model.
- Authors
Hamzavi, Iltefat; Shiff, Natalie; Martinka, Magda; Huang, Zhiwei; McLean, David; Zeng, Haishan; Lui, Harvey
- Abstract
Spectroscopic methods have been used to analyze in vivo melanin in the past but the specific effect of melanin depth on autofluorescence and reflectance spectroscopy has not been determined. In patients with blue vitiligo, three distinctive clinicopathologic patterns are present: (1) normal skin with normal epidermal melanin pigmentation (2), skin of blue vitiligo with dermal melanin pigmentation, and (3) tissue of regular vitiligo with no melanin pigmentation. Blue vitiligo may thus serve as an in vivo model to assess dermal pigment using spectroscopic techniques.
- Publication
Photodermatology, photoimmunology & photomedicine, 2006, Vol 22, Issue 1, p46
- ISSN
0905-4383
- Publication type
Journal Article
- DOI
10.1111/j.1600-0781.2006.00195.x