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- Title
The human vomeronasal organ: prenatal development stages and distribution of luteinizing hormone-releasing hormone.
- Authors
Kjær, Inger; Hansen, Birgit Fischer
- Abstract
The purpose of this study was to describe in 49 normal human prenatal specimens, 15-156 mm crown-rump length (CRL), the histomorphological development of the bilateral vomeronasal organ localized in the mucosa of the nasal septum. In addition, immunohistochemical localization of luteinizing hormone-releasing hormone (LHRH) was undertaken. The material was classified into five developmental stages (NAS I/V), based on the morphology of the nasal cavity. The vomeronasal organ was visible in stages NAS II. III and IV, corresponding to 21-102 mm CRL. Positive immunohistochemical reaction for LHRH neurons was pronounced in the vorneronasal organ in NAS II and Ill, corresponding approximately to fetal ages 8-12 gestational weeks (21- 5 I mm CRL). The study demonstrates in normal human prenatal material that LHRH can be recorded in the bilateral vomeronasal organs during approximately 4 weeks of intrauterine life.
- Publication
European Journal of Oral Sciences, 1996, Vol 104, Issue 1, p34
- ISSN
0909-8836
- Publication type
Academic Journal
- DOI
10.1111/j.1600-0722.1996.tb00043.x