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- Title
Effects of small interfering RNAs targeting Fascin on gene expression in oral cancer cells.
- Authors
Chen, Su-Feng; Lin, Chi-Yu; Chang, Yun-Ching; Li, Jhy-Wei; Fu, Earl; Chang, Fei-Ni; Lin, Yu-Lu; Nieh, Shin
- Abstract
Oral squamous cell carcinoma (OSCC) is one of the most common head and neck cancers. The prognosis of OSCC is usually poor because of extensive local invasion at initial diagnosis. In the literature, Fascin has been reported responsible for cell motility and over-expression of Fascin contributes to an unfavorable clinical course. Nevertheless, the roles of Fascin protein playing in aggressiveness of OSCC and their potential mechanisms need to be elucidated.
- Publication
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2009, Vol 38, Issue 9, p722
- ISSN
1600-0714
- Publication type
Journal Article
- DOI
10.1111/j.1600-0714.2009.00769.x