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- Title
Familial monoclonal gammopathy: hyper-responsive B cells in unaffected family members.
- Authors
Steingrímsdóttir, Hlíf; Einarsdóttir, Helga K; Haraldsdóttir, Vilhelmína; Ogmundsdóttir, Helga M
- Abstract
In Iceland, eight families have been identified with multiple cases of monoclonal gammopathies (MG) and other lymphoproliferative diseases. In one of these families with several cases of monoclonal gammopathy of undetermined significance (MGUS) and Waldenströms macroglobulinemia, in vitro stimulation with poke-weed mitogen revealed hyper-responsive B cells showing increased immunoglobulin production in one-third of disease-free family members.
- Publication
European journal of haematology, 2011, Vol 86, Issue 5, p396
- ISSN
1600-0609
- Publication type
Journal Article
- DOI
10.1111/j.1600-0609.2011.01593.x