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- Title
Karyotype complements the International Prognostic Scoring System for primary myelofibrosis.
- Authors
Hussein, Kebede; Huang, Jocelin; Lasho, Terra; Pardanani, Animesh; Mesa, Ruben A; Williamson, Cynthia M; Ketterling, Rhett P; Hanson, Curtis A; Van Dyke, Daniel L; Tefferi, Ayalew
- Abstract
The International Prognostic Scoring System (IPSS) for primary myelofibrosis (PMF) is based on five independent predictors of inferior survival: age >65 yr, hemoglobin <10 g/dL, leukocyte count >25 x 10(9)/L, circulating blasts > or =1%, and presence of constitutional symptoms. The presence of 0, 1, 2, and > or =3 adverse factors defines low, intermediate-1, intermediate-2, and high risk disease, respectively. We examined the additional prognostic relevance of karyotype.
- Publication
European journal of haematology, 2009, Vol 82, Issue 4, p255
- ISSN
1600-0609
- Publication type
Journal Article
- DOI
10.1111/j.1600-0609.2009.01216.x