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- Title
Sensitivity and specificity of the nickel spot (dimethylglyoxime) test.
- Authors
Thyssen, Jacob P; Skare, Lizbet; Lundgren, Lennart; Menné, Torkil; Johansen, Jeanne D; Maibach, Howard I; Lidén, Carola
- Abstract
The accuracy of the dimethylglyoxime (DMG) nickel spot test has been questioned because of false negative and positive test reactions. The EN 1811, a European standard reference method developed by the European Committee for Standardization (CEN), is fine-tuned to estimate nickel release around the limit value of the EU Nickel Directive from products intended to come into direct and prolonged skin contact. Because assessments according to EN 1811 are expensive to perform, time consuming, and may destruct the test item, it should be of great value to know the accuracy of the DMG screening test.
- Publication
Contact dermatitis, 2010, Vol 62, Issue 5, p279
- ISSN
1600-0536
- Publication type
Journal Article
- DOI
10.1111/j.1600-0536.2010.01709.x