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Title
Augmentation of antidepressants with atypical antipsychotics for treatment-resistant major depressive disorder.
Authors
Shelton, Richard C; Papakostas, George I
Abstract
Atypical antipsychotics (AAPs) have been hypothesized to be beneficial in treatment-resistant depression (TRD). This paper will review a biochemical rationale and will summarize the data regarding the effectiveness of AAPs in TRD.