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- Title
Regulation of alpha7-nicotinic receptor subunit and alpha7-like gene expression in the prefrontal cortex of patients with bipolar disorder and schizophrenia.
- Authors
De Luca, V; Likhodi, O; Van Tol, H H M; Kennedy, J L; Wong, A H C
- Abstract
The alpha7-nicotinic receptor subunit gene (CHRNA7) is located at chromosome 15q13-14, a region previously linked with schizophrenia. Genetic association and mRNA expression studies also implicate CHRNA7 in schizophrenia. The CHRNA7 gene has a partial duplication that constitutes the alpha7-like nicotinic receptor gene (CHRFAM7A). We hypothesized that major psychoses could affect the expression of both CHRNA7 and CHRFAM7A.
- Publication
Acta psychiatrica Scandinavica, 2006, Vol 114, Issue 3, p211
- ISSN
0001-690X
- Publication type
Journal Article
- DOI
10.1111/j.1600-0447.2006.00785.x