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- Title
Early predictors of anemia in patients with hepatitis C genotype 1 treated with peginterferon alfa-2a (40KD) plus ribavirin.
- Authors
Reau, Nancy; Hadziyannis, Stephanos J; Messinger, Diethelm; Fried, Michael W; Jensen, Donald M
- Abstract
Adherence to ribavirin is one factor that is critically important in the treatment of hepatitis C virus infection. However, ribavirin can be associated with clinically significant hemolytic anemia resulting in dose modifications in up to one-quarter of patients. Currently, baseline predictors of considerable anemia are not sufficiently discriminating for routine therapeutic intervention. The objective of this analysis was to elucidate baseline and on-treatment factors predictive of a considerable hemoglobin drop at week 4.
- Publication
The American journal of gastroenterology, 2008, Vol 103, Issue 8, p1981
- ISSN
1572-0241
- Publication type
Journal Article
- DOI
10.1111/j.1572-0241.2008.01957.x