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- Title
Homocysteine triggers mucosal microvascular activation in inflammatory bowel disease.
- Authors
Danese, Silvio; Sgambato, Alessandro; Papa, Alfredo; Scaldaferri, Franco; Pola, Roberto; Sans, Miquel; Lovecchio, Maria; Gasbarrini, Giovanni; Cittadini, Achille; Gasbarrini, Antonio
- Abstract
Increased homocysteine contributes to the pathophysiology of several chronic inflammatory diseases. Whether homocysteine could participate in mucosal inflammation in inflammatory bowel disease (IBD) has not been explored yet. Our aims were to study the levels of plasma and mucosal homocysteine in IBD patients and to assess whether homocysteine can trigger an inflammatory reaction on human intestinal microvascular endothelial cells (HIMECs).
- Publication
The American journal of gastroenterology, 2005, Vol 100, Issue 4, p886
- ISSN
0002-9270
- Publication type
Journal Article
- DOI
10.1111/j.1572-0241.2005.41469.x