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- Title
The familial Mediterranean fever (MEVF) gene as a modifier of Crohn's disease.
- Authors
Fidder, Herma; Chowers, Yehuda; Ackerman, Zvi; Pollak, Rivka Dresner; Crusius, J Bart A; Livneh, Avi; Bar-Meir, Simon; Avidan, Benjamin; Shinhar, Yael
- Abstract
Crohn's disease (CD) has been reported to be more frequent among non-Ashkenazi Jewish patients suffering from familial Mediterranean fever (FMF). Interestingly, functional similarities between the CD susceptibility gene (NOD2/CARD15) and the FMF gene (MEFV) have been described: both belong to the death domain containing protein family, important in the regulation of apoptosis, cytokine processing and inflammation.
- Publication
The American journal of gastroenterology, 2005, Vol 100, Issue 2, p338
- ISSN
0002-9270
- Publication type
Journal Article
- DOI
10.1111/j.1572-0241.2005.40810.x