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- Title
Cascara sagrada-induced intrahepatic cholestasis causing portal hypertension: case report and review of herbal hepatotoxicity.
- Authors
Nadir, A; Reddy, D; Van Thiel, D H
- Abstract
Herbal medicines are gaining widespread popularity. Much of the public believes that botanical herbs are both harmless and useful for the treatment of a variety of symptoms. This belief stands in contrast with the fact that many herbal therapies have been shown to be toxic. In the present case report, cascara sagrada (CS) has been associated with the development of cholestatic hepatitis, complicated by portal hypertension. CS is a mixture of ingredients, among which is anthracene glycoside--an herbal agent that previously has been associated with chronic hepatitis. The liver injury in the case herein reported is believed to be related to either anthracene glycoside or one of the other constituents of CS.
- Publication
The American journal of gastroenterology, 2000, Vol 95, Issue 12, p3634
- ISSN
0002-9270
- Publication type
Journal Article
- DOI
10.1111/j.1572-0241.2000.03386.x