We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Power Calculation for Case–Cohort Studies with Nonrare Events.
- Authors
Jianwen Cai; Donglin Zeng
- Abstract
Case–cohort design has been advocated in many epidemiologic studies when studying rare diseases or events. In this design, with a rare event, all the events are selected for risk-factor assessment. When the event is not rare, it is desirable to consider a generalized case–cohort design, where only a fraction of events are sampled. We provide a valid test statistic to compare hazards functions between two samples for this generalized design and give a method for calculating power. Our result generalizes the result in Cai and Zeng (2004, Biometrics 60, 1015–1024), and it shows numerically that efficiency loss due to sampling only part of the events is very low under nonrare-events situation.
- Publication
Biometrics, 2007, Vol 63, Issue 4, p1288
- ISSN
0006-341X
- Publication type
Academic Journal
- DOI
10.1111/j.1541-0420.2007.00838.x