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- Title
Neutrophil extracellular traps promote deep vein thrombosis in mice.
- Authors
Brill, A; Fuchs, T A; Savchenko, A S; Thomas, G M; Martinod, K; De Meyer, S F; Bhandari, A A; Wagner, Denisa D
- Abstract
Upon activation, neutrophils can release nuclear material known as neutrophil extracellular traps (NETs), which were initially described as a part of antimicrobial defense. Extracellular chromatin was recently reported to be prothrombotic in vitro and to accumulate in plasma and thrombi of baboons with experimental deep vein thrombosis (DVT).
- Publication
Journal of thrombosis and haemostasis : JTH, 2012, Vol 10, Issue 1, p136
- ISSN
1538-7836
- Publication type
Journal Article
- DOI
10.1111/j.1538-7836.2011.04544.x