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- Title
Human leukocyte antigen association in idiopathic thrombotic thrombocytopenic purpura: evidence for an immunogenetic link.
- Authors
Scully, M; Brown, J; Patel, R; McDonald, V; Brown, C J; Machin, S
- Abstract
Thrombotic thrombocytopenic purpura (TTP) is a rare, acute, life-threatening disorder, associated with a deficiency in ADAMTS 13. The majority of acute, idiopathic, adult TTP cases are associated with anti-ADAMTS 13 IgG antibodies. However, the factor(s) precipitating an acute TTP episode are not always obvious; indeed, a multifactorial etiology is likely.
- Publication
Journal of thrombosis and haemostasis : JTH, 2010, Vol 8, Issue 2, p257
- ISSN
1538-7836
- Publication type
Journal Article
- DOI
10.1111/j.1538-7836.2009.03692.x