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- Title
Ability of VKORC1 and CYP2C9 to predict therapeutic warfarin dose during the initial weeks of therapy.
- Authors
Ferder, N S; Eby, C S; Deych, E; Harris, J K; Ridker, P M; Milligan, P E; Goldhaber, S Z; King, C R; Giri, T; McLeod, H L; Glynn, R J; Gage, B F
- Abstract
CYP2C9 and VKORC1 genotypes predict therapeutic warfarin dose at initiation of therapy; however, the predictive ability of genetic information after a week or longer is unknown. Experts have hypothesized that genotype becomes irrelevant once international normalized ratio (INR) values are available because INR response reflects warfarin sensitivity.
- Publication
Journal of thrombosis and haemostasis : JTH, 2010, Vol 8, Issue 1, p95
- ISSN
1538-7836
- Publication type
Journal Article
- DOI
10.1111/j.1538-7836.2009.03677.x