We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Molecular defects in ITGA2B and ITGB3 genes in patients with Glanzmann thrombasthenia.
- Authors
Kannan, M; Ahmad, F; Yadav, B K; Kumar, R; Choudhry, V P; Saxena, R
- Abstract
Glanzmann thrombasthenia (GT) is an autosomal recessive inherited platelet function defect that is characterized by reduction in, or absence of, platelet aggregation in response to multiple physiologic agonists. The defect is caused by mutations in the genes encoding ITGA2B or ITGB3. This results in qualitative or quantitative abnormalities of the platelet receptor, alpha IIb-beta 3.
- Publication
Journal of thrombosis and haemostasis : JTH, 2009, Vol 7, Issue 11, p1878
- ISSN
1538-7836
- Publication type
Journal Article
- DOI
10.1111/j.1538-7836.2009.03579.x