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- Title
The membrane-proximal intermolecular disulfide bonds in glycoprotein Ib influence receptor binding to von Willebrand factor.
- Authors
Mo, X; Luo, S-Z; Munday, A D; Sun, W; Berndt, M C; López, J A; Dong, J-F; Li, R
- Abstract
In the platelet glycoprotein (GP)Ib-IX complex, the binding site for its ligand von Willebrand factor (VWF) is restricted to the N-terminal domain of the GPIbalpha subunit. How the other subunits in the complex, GPIbbeta and GPIX, regulate the GPIbalpha-VWF interaction is not clear.
- Publication
Journal of thrombosis and haemostasis : JTH, 2008, Vol 6, Issue 10, p1789
- ISSN
1538-7836
- Publication type
Journal Article
- DOI
10.1111/j.1538-7836.2008.03088.x