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Title
A novel nitric oxide-releasing statin derivative exerts an antiplatelet/antithrombotic activity and inhibits tissue factor expression.
Authors
Rossiello, M R; Momi, S; Caracchini, R; Giannini, S; Guglielmini, G; Monopoli, A; Ongini, E; Semeraro, N; Colucci, M; Gresele, P
Abstract
NO-releasing statins are new chemical entities, combining HMG-CoA reductase inhibition and slow NO release, that possess stronger anti-inflammatory and antiproliferative activities than the native statins.
Publication
Journal of thrombosis and haemostasis : JTH, 2005, Vol 3, Issue 11, p2554