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- Title
Red blood cell endothelial nitric oxide synthase does not modulate red blood cell storage hemolysis.
- Authors
Kanias, Tamir; Wang, Ling; Lippert, Ashley; Kim-Shapiro, Daniel B; Gladwin, Mark T
- Abstract
The red blood cell (RBC) endothelial nitric oxide synthase (eNOS) has been shown to regulate intrinsic RBC rheologic properties, such as membrane deformability, suggesting that a functional eNOS could be important in RBC viability and function during storage. This study examines the correlation between RBC eNOS deficiency and the propensity of RBCs to hemolyze under selected stress conditions including prolonged hypothermic storage.
- Publication
Transfusion, 2013, Vol 53, Issue 5, p981
- ISSN
1537-2995
- Publication type
Journal Article
- DOI
10.1111/j.1537-2995.2012.03850.x