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- Title
Expression of growth differentiation factor 15 is not elevated in individuals with iron deficiency secondary to volunteer blood donation.
- Authors
Tanno, Toshihiko; Rabel, Antoinette; Lee, Y Terry; Yau, Yu Ying; Leitman, Susan F; Miller, Jeffery L
- Abstract
Low serum hepcidin levels provide a physiologic response to iron demand in patients with iron deficiency (ID). Based on a discovery of suppressed hepcidin expression by a cytokine named growth differentiation factor 15 (GDF15), it was hypothesized that GDF15 may suppress hepcidin expression in humans with ID due to blood loss.
- Publication
Transfusion, 2010, Vol 50, Issue 7, p1532
- ISSN
1537-2995
- Publication type
Journal Article
- DOI
10.1111/j.1537-2995.2010.02601.x