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- Title
Suboptimal effect of a three-factor prothrombin complex concentrate (Profilnine-SD) in correcting supratherapeutic international normalized ratio due to warfarin overdose.
- Authors
Holland, Lorne; Warkentin, Theodore E; Refaai, Majed; Crowther, Mark A; Johnston, Marilyn A; Sarode, Ravindra
- Abstract
Plasma transfusion is standard therapy for urgent warfarin reversal in the United States. "Four-factor" prothrombin complex concentrate (PCC), available in Europe, has advantages over plasma therapy for warfarin reversal; however, only "three-factor" PCCs (containing relatively low Factor [F]VII) are available in the United States.
- Publication
Transfusion, 2009, Vol 49, Issue 6, p1171
- ISSN
1537-2995
- Publication type
Journal Article
- DOI
10.1111/j.1537-2995.2008.02080.x