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- Title
DCS-1, DCS-2, and DFV share amino acid substitutions at the extracellular RhD protein vestibule.
- Authors
Flegel, Willy A; von Zabern, Inge; Doescher, Andrea; Wagner, Franz F; Vytisková, Jindra; Písacka, Martin
- Abstract
RhD and RhCE are structurally related to ammonium transporter proteins, yet their physiologic function remains unclear. Recent three-dimensional homology modeling with Escherichia coli AmtB as a template defined a putative transmembraneous channel. Three RhD variants with amino acid substitutions located at the extracellular channel aperture are described.
- Publication
Transfusion, 2008, Vol 48, Issue 1, p25
- ISSN
0041-1132
- Publication type
Journal Article
- DOI
10.1111/j.1537-2995.2007.01506.x