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- Title
Weak blood group B phenotypes may be caused by variations in the CCAAT-binding factor/NF-Y enhancer region of the ABO gene.
- Authors
Seltsam, Axel; Wagner, Franz F; Grüger, Daniela; Gupta, Christa D; Bade-Doeding, Christina; Blasczyk, Rainer
- Abstract
Binding of CCAAT-binding factor NF-Y (CBF/NF-Y) to a 43-bp repeat unit in the minisatellite region in the 5' region of the ABO gene (CBF/NF-Y enhancer region) plays an important role in regulating the transcription of ABO genes. The common ABO alleles were found to have CBF/NF-Y enhancer regions with specific numbers of 43-bp minisatellite repeats.
- Publication
Transfusion, 2007, Vol 47, Issue 12, p2330
- ISSN
0041-1132
- Publication type
Journal Article
- DOI
10.1111/j.1537-2995.2007.01475.x